Prof. dr. H.A.B. (Han) Wösten

Hugo R. Kruytgebouw
Padualaan 8
Kamer O.401
3584 CH Utrecht

Prof. dr. H.A.B. (Han) Wösten

Professor
Molecular Microbiology
+31 30 253 3448
h.a.b.wosten@uu.nl

Curriculum Vitae H.A.B. Wösten
 

Education

Bachelor & Master Education     :Biology (1984-1989), Groningen University (top 5%)

PhD                                        :Biology (1989-1994). Excretion of proteins during fungal growth                                                    and development, Groningen University (top 5%)                                                                

Work experience

Post-doc                                 :Munich University (1994 – 1995) with an EMBO long term

                                               fellowship

Post-doc                                 :Groningen University (1995-1998)                                                      

Assistant professor                  :Groningen University (1998-2001)

Full professor                          :Utrecht University (2001-present)                                               

 

Management

Projectleader                           :BioMaDe Technology (2000-2001)

Project leader                          :TiFN (2016-present)

Member Management Team      :Kluyver Centre Genomics of Industrial Fermentation (2010-2013)

Member Management Team      :BE-BASIC (2013-2017)

Head Department of Biology     :Utrecht University (2011-2017)

Director Bachelor Biology          :Utrecht University (2017-present) (1100 students)

Director Master Biosciences       :Utrecht University (2017-2019) (700 students)

Vice chair Executive Board         :Graduate School of Lie Sciences Utrecht University (2017-2019)

                                               (1400 Master students; 1800 PhD students)

-President of the Royal Netherlands Society for Microbiology (2009-2017) (1500 members)

-Chair Mycology Division Royal Netherlands Society for Microbiology (2008-2017)

-Royal Netherlands Society for Microbiology Representative Federation of European Microbiological Societies (FEMS) (2017- 2018)

-Editor Antonie van Leeuwenhoek Journal of Microbiology (2005-present)

-Editor Nature Scientific Reports (2018-present)

-Chair (1) and member (11) of evaluation committees of the Netherlands Science Council NWO (1), The Netherlands Technology Foundation STW (10), and the German Science Council DFG (1).

 

Consultancy

-BioMaDe Technology Foundation (2001-2008)

-Procter & Gamble (2017-present)

 

Awards and Recognition
-Unilever Research Award 1989 (1800 €)                                    

-Netherlands Society for Biochemistry and Molecular Biology Award 1999 (1600 €)

-STW PIONIER 2001 (900.000 €)

-STW Simon Stevin Meester Award 2008 (500.000 €)

-Designers & Artists 4 Genomics Award DA4GA 2010 (25.000 €). “Systems Synthetics” (together with Maurizio Montalti)

-ZonMW BioArt & Design Award 2014 (25.000 €). “Growing Food from Toxic Waste”(together with Katharina Unger and Julia Kaisinger)

-ZonMW BioArt & Design Award 2017 (25.000 €). “Mother's Hand Taste (Son-mat)” (together with Ji Won Woo

-National Biology Research Review 2010: Excellent (Quality, Relevance, Viability, Productivity)

 

Promotor of PhD students

I was promotor of 30 PhD students (2004- present)

 

Publications and Patents

-I was (co-)author of  >170 publications with publications in Nature (1), Nature Biotechnology (2) and Nature Reviews Microbiology (1)

-My H- factor is 56 (Google Scholar), 48 (Scopus), 46 (Web of Science)

-I am inventor of 4 patents and 7 patent applications

 

International Conferences

I (co-)organized > 10 international conferences, chaired 8 sessions and gave >25 lectures including 4 key note lectures

 

Granted projects (> 75.000 €)

-STW PIONIER (2001). The fungal protein factor. Increasing the number of production facilities and production units.

-STW (2004). Master switches of initiation of mushroom formation.

-STW (2005). Control of Verticillium fungicola on mushroom (P.A.H.M. Bakker, L.C. van Loon, G.A. Veldink, L.G. Lugones, H.A.B. Wösten)

-STW (2006). Hyper production of proteins in filamentous fungi by increasing the number of secreting hyphae (H.A.B. Wösten and W.H. Müller).

-STW (2007). Production of therapeutic proteins in mushroom (L.G. Lugones, H.J. Bosch, H. Sprong, H.A.B. Wösten)

-IOP Genomics (2007). The Dynamics of the Fungal Mycelium (M.J.E.C. van der Maarel, H.A.B. Wösten, C.A.M.J.J. van den Hondel, H. Stam, M de Boer).

-STW (2007). Modification of the expression of transcriptional regulators of Aspergillus to improve industrial fermentations and use of agricultural by-products (R.P. de Vries, H.A.B. Wösten, A.F.J. Ram).

-Kluyver Centrum Netherlands Genomics Initiative (2007). Genomics of Filamentous Fungi: Understanding and engineering of key cellular processes responsible for the highly efficient production of fungal proteins and non-ribosomal peptides. (H.A.B Wösten, R.A.L. Bovenberg, A.J.M. Driessen, I.J. van der Klei, A.F.M Ram).

-ALW (2007). Intercellular streaming of proteins via cytoplasmic connections (H.A.B. Wösten)

-NCSB/STW (2010). The effect of aging of the mycelium on the expression profile of newly formed Aspergillus niger hyphae (H.A.B. Wösten, A.F. Ram en M. Reinders).

-STW (2010). How mushrooms feed on sugar (HAB Wösten, LG Lugones, RP de Vries en H Schols).

-STW (2010). Heterogeneity of the fungal mycelium in an industrial fermentation (HAB Wösten).

-STW (2010). Indoor fungal growth and humidity dynamics (OCG Adan, J. Dijksterhuis, HAB Wösten, H.C. Gerritsen).

-STW (2011). Push the white button; controlling mushroom formation (HAB Wösten; LG Lugones; ASM Sonnenberg en MJT Reinders).

-BASF (2011). Schizophyllan biosynthesis in Schizophyllum commune.

-NWO Creatieve Industrie (embedded research) (2013) Mycelium design (HAB Wösten).

-BE BASIC (2013) Regulation of enzyme production in fungal cell factories (HAB Wösten, AFJ Ram, RP de Vries).

-ALW (2013) Identity of compartments within a fungal hypha (HAB Wösten).

-STW RTD program (2015) Mycelium-based materials for product design (HAB Wösten, M Montalti, E Karama).

-TIFN (2016) Heterogeneity in spores of food spoilage fungi (HAB Wösten, RA Ohm, J. Dijksterhuis,; J. Houbraken, AFJ Ram).

-STW (2017) Traffic control: optimal flow of nutrients to developing mushrooms.

-OASEN/UU (2018) Waste water treatment with mushroom forming fungi.

 

Outreach

-I co-organized 3 exhibitions one of which (Fungal Futures) was opened by the Minister of Education, Culture and Sciences

-My work was topic of (inter)national radio (17 times ), (inter)national television (11 times), (inter)national news papers (18 times), online journals (10 times)